Wednesday, April 27, 2011

Meditation & Telomeres

"Epel has been collaborating with UCSF's Elizabeth Blackburn, who shared the 2009 Nobel physiology or medicine prize for her work on telomeres, to investigate whether telomeres are affected by psychological factors. They found that at the end of the retreat, meditators had significantly higher telomerase activity than the control group, suggesting that their telomeres were better protected. The researchers are cautious, but say that in theory this might slow or even reverse cellular ageing. "If the increase in telomerase is sustained long enough," says Epel, "it's logical to infer that this group would develop more stable and possibly longer telomeres over time."


Pagnoni has previously used brain imaging to show that meditation may protect against the cognitive decline that occurs as we age. But the Shamatha project is the first to suggest that meditation plays a role in cellular ageing. If that link is confirmed, he says, "that would be groundbreaking".


So how could focusing on your thoughts have such impressive physical effects? The assumption that meditation simply induces a state of relaxation is "dead wrong", says Raison. Brain-imaging studies suggest that it triggers active processes within the brain, and can cause physical changes to the structure of regions involved in learning, memory, emotion regulation and cognitive processing.


The question of how the immaterial mind affects the material body remains a thorny philosophical problem, but on a practical level, "our understanding of the brain-body dialogue has made jaw-dropping advances in the last decade or two," says Raison. One of the most dramatic links between the mind and health is the physiological pathways that have evolved to respond to stress, and these can explain much about how meditation works."

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