Sunday, September 21, 2014

Random Noise in Biology

Noise sounds like bad news for biology. How can a plant or animal organize its development and behavior when all the processes involved are inherently messy? Indeed, sometimes noise causes real problems. For instance, researchers from the Scott Rifkin lab at the University of California–San Diego have shown that when a certain strain of completely identical, genetically engineered nematode worms are raised in the same environment, some will develop normally while others spontaneously die. In this case, noise means the difference between life and death.

Usually the effects of noise are not so dire. Most organisms have evolved systems to protect themselves from noise. And in fact, biologists have begun to understand that in some cases noise can be a good thing. Cells, organisms, and populations exploit this seemingly detrimental feature of the natural world, sometimes in surprisingly ingenious ways.

[---]

Genetic determinism is the view that our genes make us who we are. Popular articles abound describing genes for daredevilishness, creativity, empathy, even being a Republican. Futurists and science-fiction authors predict that genetic engineering will someday allow designer children, built to order, with whatever smarts, looks, and personalities their parents prefer. But biology’s new recognition of the role of noise in development gives us one more reason to think that this simply isn’t going to happen. Gene mapping can’t tell you whether or not your kid will be a skydiver or a conservative, because gene expression is a far more complex phenomenon than biologists long imagined. Even if we can get the genes right, and somehow completely control environments, there will always be noise to make life richly unpredictable.


- More Here

No comments: