A new analysis conducted at Forbes puts grim numbers on these costs. A
company hoping to get a single drug to market can expect to have spent
$350 million before the medicine is available for sale. In part because
so many drugs fail, large pharmaceutical companies that are working on
dozens of drug projects at once spend $5 billion per new medicine.
A 2012 article in Nature Reviews Drug Discovery says the number of drugs invented per billion dollars of R&D invested has been cut in half every nine years for half a century. Reversing this merciless trend has caught the attention of the U.S. government. Francis Collins, the director of the National Institutes of Health, in 2011 started a new National Center for Advancing Translational Sciences to remove the roadblocks that keep new drugs from reaching patients.
“One point your numbers tell you is how horrendous the failure rate is and how that causes the cost of success to be so much higher,” says Collins. “We would love to contribute to making that failure rate lower, to identifying those bottlenecks and to trying to reengineer the pipeline so if failures happen, they happen very early and not in later stages where the costs are higher.”
The good news is that a close look at the data we collected provides some hints as to how to improve the industry’s hit rate – and how individual companies, without lowering the overall cost of developing a drug, can at least reduce their own expenses. Some companies – like Bristol-Myers Squibb, Regeneron Pharmaceuticals, and Aegerion – do far better than their peers.
- More Here
A 2012 article in Nature Reviews Drug Discovery says the number of drugs invented per billion dollars of R&D invested has been cut in half every nine years for half a century. Reversing this merciless trend has caught the attention of the U.S. government. Francis Collins, the director of the National Institutes of Health, in 2011 started a new National Center for Advancing Translational Sciences to remove the roadblocks that keep new drugs from reaching patients.
“One point your numbers tell you is how horrendous the failure rate is and how that causes the cost of success to be so much higher,” says Collins. “We would love to contribute to making that failure rate lower, to identifying those bottlenecks and to trying to reengineer the pipeline so if failures happen, they happen very early and not in later stages where the costs are higher.”
The good news is that a close look at the data we collected provides some hints as to how to improve the industry’s hit rate – and how individual companies, without lowering the overall cost of developing a drug, can at least reduce their own expenses. Some companies – like Bristol-Myers Squibb, Regeneron Pharmaceuticals, and Aegerion – do far better than their peers.
- More Here
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