VICT3R Project: What Are the Goals of Virtual Rabbits?

Animals used in laboratories are often treated as mere objects, enduring painful procedures like burns, poisoning, food deprivation, and skin, eye, and ear lacerations—all in the name of human safety. While many argue that these tests are necessary for ensuring product safety, ethical alternatives exist, and they should be explored. That’s where the Spanish university’s virtual rabbit initiative comes in.

The primary goal of the VICT3R project is to significantly reduce the number of animals used in safety testing for drugs and other chemicals by replacing them with computer-generated virtual models. This represents a crucial milestone in the quest for ethical and sustainable scientific research. If successful, the project could  prove that virtual models can yield reliable scientific results without harming living creatures.

Scientific advancements have provided more humane -and incredibly scientific- alternatives to animal testing, such as computer simulations and human tissue models. These methods can offer effective results without harming living creatures like rabbits. The VICT3R project introduces additional key objectives:

• Reducing Animal Use: The European VICT3R project aims to reduce the total number of animals used in experiments by up to 25%. This could lead to fewer animals being subjected to tests for medicine and chemical safety.
• Data Reuse and Sharing: The project promotes reusing and sharing data and applying new data science techniques to further implement the 3Rs—reduce, refine, and replace—in preclinical animal experimentation.
• Generative AI for Synthetic Animals: In cases where historical data on certain species or conditions is unavailable, generative AI could create fully synthetic virtual animals to fill the gaps.
• Expansion to Other Studies: The aspiration of the VICT3R project is to extend this concept of virtual control groups to other toxicological and pharmacological studies, both in academic and industrial settings, further reducing reliance on animal testing.

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