Another example of epistemic humility; we have not even scratched the surface of knowledge (leave alone humans who act like they have passed the end of knowledge).
Viroids are small, infectious, and circular RNA molecules that are distinct from typical viruses. Unlike viruses, viroids do not possess a protective protein coat. They were initially discovered in plants, causing various diseases, and were later identified in fungi. Viroids are known for their ability to replicate autonomously within host cells, co-opting cellular machinery for their own reproduction.
Initially believed to exclusively infect plants, recent research suggests viroids may extend their reach to other hosts, including animals, fungi, or bacteria. In the current study, researchers delved into the genes of microbes inhabiting the human body, exploring the potential existence of viroids in this domain. They termed newly found viroids “Obelisks” due to their predicted 3D structure resembling a thin rod when they fold onto themselves.
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Recently discovered Obelisks appeared to include instructions for replication enzymes, rendering them more intricate than previously described viroids. However, akin to most viroids, they still lacked directives for a protective outer shell. The impact of these viroids on human health remains uncertain, although they could potentially influence the human microbiome by infecting bacteria. Additionally, ongoing discussions surround the evolutionary relationship between viruses and viroids — fueling the debate & questioning whether viruses evolved from viroids or vice versa.
In essence, these recent discoveries not only add layers to our understanding of human anatomy but also underscore the ongoing process of discovery and refinement in the field of medical science. The impact lies in the potential to enhance our ability to diagnose, treat, and prevent various health conditions through a more comprehensive understanding of the human body’s intricate workings.
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