Friday, December 21, 2012

Best Books of 2012

My only resolution for this year was to read as much as I could on stoicism and for once, I lived up to that promise. But ironically, none of the books on stoicism (albeit being brilliant) made the list.

First on the list is none other than the last book by Christopher Hitchens - Mortality (more here).
  • Only OK if I say something objective and stoical: I am remarking that a time might come when I’d have to let go: Carol asking about Rebecca’s wedding “Are you afraid you won’t see England again?” Also, ordinary expressions like “expiration date”… will I outlive my Amex? My driver’s license? People say— I’m in town on Friday: will you be around? WHAT A QUESTION!
  • Myself, I love the imagery of struggle. I sometimes wish I were suffering in a good cause, or risking my life for the good of others, instead of just being a gravely endangered patient. Allow me to inform you, though, that when you sit in a room with a set of other finalists, and kindly people bring a huge transparent bag of poison and plug it into your arm, and you either read or don’t read a book while the venom sack gradually empties itself into your system, the image of the ardent soldier or revolutionary is the very last one that will occur to you. You feel swamped with passivity and impotence: dissolving in powerlessness like a sugar lump in water.
  • REMEMBER, YOU TOO ARE MORTAL”— HIT ME AT THE top of my form and just as things were beginning to plateau. My two assets my pen and my voice— and it had to be the esophagus. All along, while burning the candle at both ends, I’d been “straying into the arena of the unwell” and now “a vulgar little tumor” was evident. This alien can’t want anything; if it kills me it dies but it seems very single-minded and set in its purpose. No real irony here, though. Must take absolute care not to be self-pitying or self-centered. Always prided myself on my reasoning faculty and my stoic materialism. I don’t have a body, I am a body. Yet consciously and regularly acted as if this was not true, or as if an exception would be made in my case. Feeling husky and tired on tour? See the doctor when it’s over! Lost fourteen pounds without trying. Thin at last. But don’t feel lighter because walking to the fridge is like a forced march. Then again, the vicious psoriasis/ excema pustules that no doctor could treat have gone, too. This must be some impressive toxin I’m taking. And a mercy for sleep purposes… but all the sleep-aids and blissful dozes seem somehow a waste of life— there’s plenty of future time in which to be unconscious.
  • “Until you have done something for humanity,” wrote the great American educator Horace Mann, “you should be ashamed to die.” I would have happily offered myself as an experimental subject for new drugs or new surgeries, partly of course in the hope that they might salvage me, but also on the Mann principle.
I probably will remember these simple lines until my final breathe to avoid any self-pity:
To the dumb question "Why me?" the cosmos barely bothers to return the reply: why not?” 

Next on the list is Antifragile: Things That Gain From Disorder by Nassim Nicholas Taleb (more here).
  • First ethical rule: If you see fraud and do not say fraud, you are a fraud.
  • My idea of the modern Stoic sage is someone who transforms fear into prudence, pain into information, mistakes into initiation, and desire into undertaking.
  • All you need is the wisdom to not do unintelligent things to hurt yourself (some acts of omission) and recognize favorable outcomes when they occur. (The key is that your assessment doesn’t need to be made beforehand, only after the outcome.)
  • The largest fragilizer of society, and greatest generator of crises, absence of “skin in the game.” At no point in history have so many non-risk-takers, that is, those with no personal exposure, exerted so much control. The chief ethical rule is the following: Thou shalt not have antifragility at the expense of the fragility of others.
And the last one on the list is an old book which I am reading currently - The 33 Strategies of War by Robert Greene.

Understand: the greatest generals, the most creative strategists, stand out not because they have more knowledge but because they are able, when necessary, to drop their preconceived notions and focus intensely on the present moment. That is how creativity is sparked and opportunities are seized. Knowledge, experience, and theory have limitations: no amount of thinking in advance can prepare you for the chaos of life, for the infinite possibilities of the moment. The great philosopher of war Carl von Clausewitz called this "friction": the difference between our plans and what actually happens. Since friction is inevitable, our minds have to be capable of keeping up with change and adapting to the unexpected. The better we can adapt our thoughts to the current circumstances, the more realistic our responses to them will be....

Think of the mind as a river: the faster it flows, the better it keeps up with the present and responds to change. The faster it flows, also the more it refreshes itself and the greater its energy. Obsessional thoughts, past experiences (whether traumas or successes), and preconceived notions are like boulders or mud in this river, settling and hardening there and damming it up. The river stops moving; stagnation sets in. You must wage constant war on this tendency in the mind.


All three books have made it to my all time favorites list; it has really been an enlightening year. A million thanks to all these brilliant minds who taught me to lead a better life and just be a better human being.

Quote of the Day

If psychology is the main cause, we should have 12 times as many psychologically disturbed people. But we don’t. The United States could do better, but we take mental disorders seriously and invest more in this area than do many peer countries.

Is America’s popular culture the cause? This is highly unlikely, as largely the same culture exists in other rich countries. Youth in England and Wales, for example, are exposed to virtually identical cultural influences as in the United States. Yet the rate of gun homicide there is a tiny fraction of ours. The Japanese are at the cutting edge of the world of video games. Yet their gun homicide rate is close to zero! Why? Britain has tough gun laws. Japan has perhaps the tightest regulation of guns in the industrialized world.


- Fareed Zakaria



Thursday, December 20, 2012

What I've Been Reading

Bunch of Amateurs: A Search for the American Character by Jack Hitt. I picked up this book to check on the progress of DIY Biology but was more than delighted to find Ben Franklin and Ivory-Billed woodpecker as well - fun read !!

Amateurs are often wrong, crazy, fraudulent, or twisted. There is typically a pomposity among amateurs that, well, one just has to get used to. They are often nerds, if younger; cranks, if slightly mature; eccentric, if aged; and— it should be said— at just about any age they can be total jackasses. But these are just the characteristics of people obsessed with a new idea, following their bliss, in love (amo, amas, amat— amateur) with one true thing. One thing that marks the amateur, the best of them, is this talent for not seeing things according to the dominant paradigm.
Amateurs are more likely to see what is actually there because there’s no money, no power, no prestige (at least not immediately) attached to seeing anything else. Amateurs mainly just want to know.

On DIY Biology:
Any major plant humans love to consume— the banana, the ear of corn, the apple, the potato, the tomato, most hot peppers— were all long ago coaxed into becoming the now seemingly fixed bounty of nature we revere. But we made them, using slow-motion synthetic biology.
“Every orchid or rose or lizard or snake is the work of a dedicated and skilled breeder. There are thousands of people, amateurs and professionals, who devote their lives to this business. Now imagine what will happen when the tools of genetic engineering become accessible to these people.” - Freeman Dyson

On Astrophysics:
Whether we are sitting in the Department of Astrophysics at Cambridge or under the night sky of Stellafane, we’re all amateurs once we get out here. Even the alleged facts that a genius like Stephen Hawking is working with are highly provisional. As I wrote these sentences, for instance, I received an e-mail alert about a new study out of the University of Durham in England that “suggests that the conventional wisdom about the content of the Universe may be wrong.”

There is no fixed American meta-narrative, but there is this ebb and flow between Adamsian veneration of piety and Franklinian love of improvisation, between Calvinist certainty and Deist doubt, between head and heart, virtuocracy and meritocracy, good character and cunning action, between security and freedom, between professionalism and amateurism.


Quote of the Day

I can't understand these chaps who go round American universities explaining how they write poems: It's like going round explaining how you sleep with your wife.

- Philip Larkin

Wednesday, December 19, 2012

Life of Pi

First, I would like to thank everyone who didn't let Night Shyamalan direct this movie.
I went in expecting a Disney version of the novel but I was in for a pleasant surprise and a visual treat !! Not many Hollywood movies open with a Tamil melody; it opened up those flood gates of nostalgia - no way for the contemporary India but my childhood India.
The movie is worth every penny just to watch that bond slowly unfold between Pi and Richard Parker. I was missing Max big time in the theatre and couldn't wait to get home fast enough.
  • Check out how Hindus, Christians and Muslims live so closely in India - giving that COEXIST bumper sticker a literal meaning (sans that liberal feel good idea to feel good about oneself).
  • Faith can be mellow without being passionate and preachy. A society filled with only reason will not only be boring but downright bad (I am saying this as person of no faith). It's ok to give the prefrontal cortex some rest.
  • No matter who we are, how much power or money we have, there will be times in life none of those matter. One should be aware of that and probably no amount of preparation can prepare us for that moment. But one can learn and adapt to be stoic even in the company of Richard Parker.
  • And of-course that human-animal bond. Thankfully, I live it everyday. Life is incomplete if you haven't experienced it. If you have no clue what I am talking about...



Can Hollywood stop using technology to make those stupid repetitive Marvel comics movies and make more movies like this one?


Quote of the Day

I often tried plays that looked recklessly daring, maybe even silly. But I never tried anything foolish when a game was at stake, only when we were far ahead or far behind. I did it to study how the other team reacted, filing away in my mind any observations for future use.

- Ty Cobb


Tuesday, December 18, 2012

What I've Been Reading

The Social Conquest of Earth by E.O.Wilson. A very very important book of  this century which pissed off too many people. I am not qualified to comment but I guess this is neither Darwin's Origin of Species nor Thomas Malthus's An Essay on the Principle of Population. Wilson's theory is important and probably will provide significant insights on understanding ourselves in decades to come. For a youngster, I think its better to read Wilson's other simple (but yet packed with wisdom) books like Biophlia and Consilience: The Unity of Knowledge before reading this one. Those earlier books of his has had a great influence on how I view the world. 


“Where do we come from?” “What are we?” “Where are we going?” Conceived in ultimate simplicity by Paul Gauguin on the canvas of his Tahitian masterpiece, these are in fact the central problems of religion and philosophy. Will we ever be able to solve them? Sometimes it seems not. Yet perhaps we can. Humanity today is like a waking dreamer, caught between the fantasies of sleep and the chaos of the real world. The mind seeks but cannot find the precise place and hour. We have created a Star Wars civilization, with Stone Age emotions, medieval institutions, and godlike technology. We thrash about. We are terribly confused by the mere fact of our existence, and a danger to ourselves and to the rest of life.

Eusocial Theory in a nutshell:


In briefest terms, a full theory of eusocial evolution will consist of a series of stages, subject to experimental verification, of which the following may be recognized: 

  • The formation of groups. 
  • The occurrence of a minimum and necessary combination of preadaptive traits in the groups, causing the groups to be tightly formed. In animals at least, the combination includes a valuable and defensible nest. The nest-dependent condition predetermines the likelihood that primitively eusocial groups will be a family— parent and offspring in insects and other invertebrates, and extended families in vertebrates. 
  • The appearance of mutations that prescribe the persistence of the group, most likely by the knockout of dispersal behavior. Evidently, a durable nest remains the key element in maintaining the prevalence. Primitive eusociality may emerge immediately due to spring-loaded preadaptations— those evolved in earlier stages that by chance cause groups to behave in a eusocial manner. 
  • In the insects, emergent traits caused by either the genesis of robot-like workers or the interaction of group members are shaped through group-level selection by environmental forces. 
  • Group-level selection drives changes in the insect colony life cycle and social structures, often to bizarre extremes, producing elaborate superorganisms. 
Given that the last two steps occur only in the insects and other invertebrates, how, then, did the human species achieve its own unique, culture-based social condition? What mark has the combined genetic and cultural process put on human nature? Stated another way, what are we? 





Steven Pinker and Richard Dawkins critique here and here. 



Quote of the Day

There's a lot to be said for quitters. Those people who are extremely good at one thing got that way by quitting almost everything else.

- Penelope Trunk, On Quitters

Monday, December 17, 2012

American Gut Project

An open-source, community driven effort to characterize the microbial diversity of the American public. Does diet matter? - American Gut Project




You are more microbes than you are mammal.  Everybody on Earth has two genomes.  You have the one you got form your Mom and Dad which you inherited.  Then you have your second genome which is all the genetic material that is packaged up in your gut and in your skin, all those microbes, and that is the genome you acquire.  It's interesting that there are only 23,000 genes in your genome but over three million genes in your gut microbiome.  So, in other words, those genes encode more instructions than your own genome.  It begs the question, "Who is in charge?"  We know that the microbiome may influence things like auto-immune disease, certain cancers, inflammatory bowel disease, colitis and rheumatoid arthritis.  So it appears that a lot of disease may be related to a shift in your gut composition.

Let’s say you want to donate. This is not a commercial lab, this is not a fee for services. It is a straight up citizen science project we’re asking you to donate to. You donate $99 for the project between now and January 7, you’re signed up, and you’ll receive a kit at your home. The kit basically amounts to an eight inch long double-headed swab, just like something that you swab your ear with.  It comes in a tube. What you’re going to do is, you’re going to wipe that across the toilet paper and you’re going to stick it back in the tube, and you’re going to mail it to us.  We’re going to process the sample. It’s going to go through DNA sequencing. All the samples go to the University of Colorado at Boulder, to Rob Knight’s lab. All that data will be processed there. It will be given a number. When you receive your kit at home,  you'll also get a questionnaire. You’ll also have a special ID number that nobody knows except you.


- Interview with Jeff Leach founder of American Gut Project.



Quote of the Day

Our comforting conviction that the world makes sense rests on a secure foundation: our almost unlimited ability to ignore our ignorance.

Daniel Kahneman, Thinking, Fast and Slow