New drug Tanezumab will be soon being labeled and marked as "panacea for pain". We all know how this goes unless we are from another planet and just visiting Earth for summer. In any case, an interesting aspect of this new drug is it handles pain via the brain.
"Studies have shown that physiology and genetics can increase pain sensitivity and one thing for certain, without the brain there is no pain.
"Studies have shown that physiology and genetics can increase pain sensitivity and one thing for certain, without the brain there is no pain.
But recently the big pharma company Pfizer has developed a new drug, tanezumab, that inhibits a protein involved in transmitting the pain signal to the brain.
This protein is called nerve growth factor (NGF.) It’s a naturally occurring protein, but its levels rise dramatically in response to some diseases and injuries. In the short-term it activates pain-signalling nerves and this results in what we feel is pain. But it can also increase the expression of neurotransmitters and this can change how sensory nerves transmit pain messages for the long-term. It’s as if NGF amplifies the pain message to the brain.
Tanezumab apparently neutralizes NGF and puts a halt to this amped-up pain signal."
No comments:
Post a Comment